Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1384 | Thyroid (non-cancer) | ECE2017

Five-year follow-up of thyroid cold nodules with somatic oncogene mutations in Hungarian patients

Tobias Balint , Balla Bernadett , Soltesz Petra , P Kosa Janos , Horanyi Janos , Jaray Balazs , Szekely Eszter , Istok Roland , Szekely Tamas , Lakatos Peter

Cold nodules are one of the most common findings on scintiscans and ultrasound examinations of the thyroid gland. About 5-10% of these nodules turn out to be histologically malignant. Our aim was to examine the predictive value of somatogenetic alterations associated with thyroid cancer in FNA samples of thyroid cold nodules being citologically benign at the beginning of the study. These alterations included single nucleotide mutations (BRAF, HRAS, NRAS, KRAS) and genetic tran...